[DOI] [PMC free article] [PubMed] [Google Scholar] 32.Amic F., Drmic D., Bilic Z., Krezic I., Zizek H., Peklic M., Klicek R., Pajtak A., Amic E., Vidovic T., et al
Check out Peters longevity chart You get into the bottom 50% of the quality of your life, in the last decade The average American lives to 80 or 81 If you dont smoke, are over 40, and arent suicidal, theres an 80% chance youll die of one of these four things: Cardiovascular and cerebrovascular disease Cancer Neurodegenerative disease Accidental deaths Peter recommends strength training, and to never stop strength training It can be the difference of breaking and not breaking your hip when youre 75 The 4 Dimensions of Health Span Cognition executive function, processing speed, short term memory Physical maintenance of muscle mass, functional movement, freedom from pain Sense of purpose and social support Capacity to cope with distress The Playbook for Living Longer The single most important thing you can do to live longer, is pick the right parents genetics can trump a lot The biggest leaps in human longevity came from sanitation developments, germ theory, and antibiotics Theres 7 things you can fiddle with food, exercise, sleep, modulation of stress, drugs, supplements, and hormones Triangulation putting together the insights for these three pillars: Looking at the data on centenarians (the people who live to be 100+), ~0.4% of people Examining non-humans (yeast, worms, flies, mice, apes etc.) experimenting and seeing how different things effect longevity Examining molecular insights with respect to longevity Example: certain cells in the body, senescents, are cells in the body programmed to do bad things
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Glycerol ( a ), lactate ( b ), pyruvate ( c ) and the lactate/pyruvate ratio ( d ) measured by GC-MS in media which was incubated for 24 hours (spent media) with 786-O cells expressing Luciferase (LUC) or Cr GPDH
